Spanish -  · Updated July 2026

How to Say Smallpox in Spanish | MostUsedWords.com

As of 2026, smallpox remains a significant part of medical history, especially in Spanish-speaking countries where eradication efforts were crucial. The Spanish translation for "smallpox" is viruela (IPA: /biˈɾwe.la/). This term refers specifically to the infectious disease caused by the Variola virus, characterized by a rash and fever.

In addition to understanding the primary translation of "smallpox" as viruela, it is important to explore regional variations and nuances associated with this term in different Spanish-speaking countries. For instance, in Mexico, smallpox can also be referred to as bubas (IPA: /ˈbuβas/) or viruela mayor (IPA: /biˈɾwe.la maˈjoɾ/). These terms are mainly used in historical or colloquial contexts. In Spain, the term "viruela" is most commonly used to refer to smallpox.

In Argentina, smallpox is often called viruela loca (IPA: /biˈɾwe.la ˈloka/), which translates to "crazy smallpox," adding a unique colloquial touch. In Colombia, the term sarampión negro (IPA: /saɾamˈpjon ˈneɣɾo/) is used, translating to "black measles" and highlighting the similarity of the rash to that of measles. Similarly, in Peru, smallpox is known as tifoidea (IPA: /ti.foˈi.ðea/) or fiebre de bola (IPA: /ˈfje.bɾe ðe ˈbo.la/), emphasizing the feverish symptoms associated with the disease.

Understanding smallpox symptoms in Spanish is also crucial. For example, "smallpox symptoms" can be translated as síntomas de viruela. Additionally, it's important to know how to refer to a disease outbreak in Spanish, such as using the term epidemia (IPA: /e.piˈðe.mja/).

To provide more context, comparing smallpox with other diseases like measles and chicken pox can be insightful. Measles is translated to sarampión (IPA: /saɾamˈpjõn/), while chicken pox is known as varicela (IPA: /baɾiˈθe.la/). These comparisons help in understanding the nuances and distinctions between similar diseases.

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How to Say "Smallpox" in Spanish: Sample Sentences

Here are five sample sentences you can use to say "smallpox" in Spanish:

  • La viruela fue una enfermedad devastadora que afectó a millones de personas en el pasado.

(Smallpox was a devastating disease that affected millions of people in the past.)

  • ¿Qué es la viruela y cómo se transmitía?

(What is smallpox, and how was it transmitted?)

  • El término 'viruela mayor' se utiliza para referirse a la variante más grave de la enfermedad.

(The term 'viruela mayor' is used to refer to the most severe variant of the disease.)

  • En algunas regiones de México, las personas también la conocen como 'bubas'.

(In some regions of Mexico, people also refer to it as 'bubas')

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